SQL30081N A communication error has been detected SQLSTATE=08001 DB2 --- toad client issue

I am facing the below error while connecting to DB with Toad client.

ERROR [08001] [IBM] SQL30081N  A communication error has been detected. Communication protocol being used: "TCP/IP".  Communication API being used: "SOCKETS".  Location where the error was detected: .  Communication function detecting the error: "selectForRecvTimeout".  Protocol specific error code(s): "0", "*", "*".  SQLSTATE=08001

I have re-started the Toad, uncataloging and cataloging is done. 

It looks toad is not viewing these settings.

All ports are enabled and there is no firewall issue.

Can any one help me to resolve this.